Carlos Alcaraz, 22, reached his eighth Grand Slam semi-final and will continue his quest for a third successive Wimbledon title.
French Open and Wimbledon champion Alcaraz, who won both of his previous meetings with Sinner this year, recovered from a slow start to wrap up victory in three hours, 21 minutes and improve his head-to-head record with the Italian to 6-4.
Four-times Grand Slam champion Alcaraz, who is gearing up to defend the French Open title later this month, fired off 24 winners in a strong performance to seal victory.
No. 1 seed Carlos Alcaraz of Spain was pushed to three sets before finishing off Dutch wild card Botic van de Zandschulp in the first round of the ABN AMRO Open.
Top seed Carlos Alcaraz overcame Croatia's Marin Cilic to reach the round of 16 at the Qatar Open.
An off-colour Alcaraz lost 6-1, 7-5 to Norway's Casper Ruud in his opening match on Monday and the 21-year-old cancelled a public training session the following day.
A distraught Lorenzo Musetti was struggling to comprehend how injury robbed him of victory against Novak Djokovic and a place in the Australian Open semi-final on Wednesday.
Top seed Carlos Alcaraz withstood a charge from qualifier Luca Nardi for a 6-1, 4-6, 6-3 victory in the second round of the Qatar ExxonMobil Open in Doha on Wednesday.
Sinner's retirement and world number one Alcaraz's withdrawal due to an ankle injury blows the draw wide open, with Djokovic in the hunt for a record-extending fifth title in Shanghai.
The event comes at a time when tennis is facing criticism over its relentless tour schedule.
Tough road for defending champion Keys
Carlos Alcaraz said he thought the trio of teenagers who have lit up the first week of the Australian Open have the skills to play the game at the top level
Sachin Tendulkar was snapped, flanked by 20-time Grand Slam champion Roger Federer and Bjorn Borg, who has won 11 majors.
Russian seventh seed Daniil Medvedev, the 2023 Miami champion who arrived this year fresh off a run to the Indian Wells semi-finals, crashed out at the first hurdle as he fell 6-2, 6-3 to Spaniard Jaume Munar.
'We heard it was like the Hollywood of mixed doubles.'
Carlos Alcaraz suffered a shock 6-1, 7-5 defeat against Norway's Casper Ruud in his opening match at the ATP Finals
Fresh off winning the Stuttgart Open by beating former world number six Matteo Berrettini, Draper put on a near flawless display
Carlos Alcaraz failed to reach the Paris Masters quarter-finals after a thrilling 6-1, 3-6, 7-5 defeat to local favourite Ugo Humbert
The Dane revealed he had taken notes from how Novak Djokovic beat Alcaraz in the Olympic final at Roland Garros.
Carlos Alcaraz reveals prize money attracted him to Saudi's Six Kings Slam
Nine of the world's top-10 men and nine of the top-10 women have officially entered into the U.S. Open's revamped mixed doubles event, tournament organisers said on Tuesday, with former singles champions Carlos Alcaraz and Emma Raducanu teaming up.
24-time Grand Slam champion Novak Djokovic looked completely powerless as he was pummeled into submission by Spain's Carlos Alcaraz.
Teichmann wins singles, Anshba-Pridankina claim doubles at Mumbai Open
Carlos Alcaraz has vowed to learn from the incident and ensure it doesn't happen again
Talk about a man in a hurry -- 10th seed Ben Shelton required just 55 seconds to finish off Australian Rinky Hijikata and reach the Wimbledon third round on Friday.
Top seed Carlos Alcaraz of Spain and No. 8 seed Hubert Hurkacz of Poland will clash in the ABN Amro Open semi-finals on Saturday after both posted victories on Friday in Rotterdam, Netherlands.
Novak Djokovic doused Dutchman Botic van de Zandschulp 6-3, 6-4, 7-6(4) at the Australian Open to reach the fourth round and add another line in the record book during his bid for a standalone 25th Grand Slam title.
The flawless performance means Djokovic has reached a century of match wins in three of the four Grand Slams, with 95 at the U.S. Open.
Rafael Nadal teamed up with Carlos Alcaraz for the first time as Spain's so-called dream team opened their Olympic doubles campaign with a 7-6(4), 6-4 defeat of Argentine sixth seeds Maximo Gonzales and Andres Molteni on Saturday.
Carlos Alcaraz reached his second Australian Open quarter-final on Sunday when his opponent Jack Draper retired injured when trailing 7-5, 6-1.
Factbox on Carlos Alcaraz, who beat Alexander Zverev
Alcaraz has not gone beyond the quarter-finals in his three previous visits to Melbourne, but that has not stopped the world number three from dreaming of glory in the Jan. 12-26 event.
Carlos Alcaraz said he enjoys a good friendship with Novak Djokovic away from the court but the Spaniard also relishes the intense rivalry
On any other occasion, there would have been a build-up of excitement from cricket fans. But not this time.
Images from Day 5 of the Wimbledon Championships, at the All England Lawn Tennis and Croquet Club, London, on Friday.
'She has been my crush since I started playing tennis. I was thrilled to see her in person. She was very charming.'
Defending champions Iga Swiatek and Carlos Alcaraz powered into the second round of the French Open on Monday.
Defending champion Jannik Sinner reached the semi-finals of the ATP Finals with a 6-4, 6-3 win over two-times winner Alexander Zverev on Wednesday, with Ben Shelton eliminated after losing earlier to Felix Auger-Aliassime in the same group.
Jannik Sinner's tennis may be making headlines, but his off-court life is drawing just as much curiosity especially after his ATP Finals win, where a smiling Laila Hasanovic was the first person he hugged.
Jannik Sinner said he had to prioritise preparations for his Australian Open title defence.